Application and evaluation of management mode for the use of antimicrobial drugs in county-level medical communities led by anti-infective clinical pharmacists

DENG Xiaoqin; ZHAO Chi; LI Zhaohong; YAN Hongyan; SHEN Dongfang; TAN Helang; JIANG Mingzhong; DENG Nanjun

doi:10.6039/j.issn.1001-0408.2024.01.17

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Application and evaluation of management mode for the use of antimicrobial drugs in county-level medical communities led by anti-infective clinical pharmacists

更新时间：2024-01-11

- Application and evaluation of management mode for the use of antimicrobial drugs in county-level medical communities led by anti-infective clinical pharmacists
- ZHONGGUO YAOFANG Vol. 35, Issue 1, Pages: 95-100(2024)
- 作者机构：
  
  重庆市忠县人民医院药剂科，重庆忠县404300
- 作者简介：
- 基金信息：
- DOI：10.6039/j.issn.1001-0408.2024.01.17
  CLC： R95
- Published：15 January 2024，
  
  Received：21 August 2023，
  
  Revised：16 November 2023，
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邓晓琴,赵池,李召红等.县域医共体以抗感染临床药师为主体的抗菌药物使用管理模式应用及评价 ^Δ[J].中国药房,2024,35(01):95-100.

DENG Xiaoqin,ZHAO Chi,LI Zhaohong,et al.Application and evaluation of management mode for the use of antimicrobial drugs in county-level medical communities led by anti-infective clinical pharmacists[J].ZHONGGUO YAOFANG,2024,35(01):95-100.
邓晓琴,赵池,李召红等.县域医共体以抗感染临床药师为主体的抗菌药物使用管理模式应用及评价 ^Δ[J].中国药房,2024,35(01):95-100. DOI： 10.6039/j.issn.1001-0408.2024.01.17.

DENG Xiaoqin,ZHAO Chi,LI Zhaohong,et al.Application and evaluation of management mode for the use of antimicrobial drugs in county-level medical communities led by anti-infective clinical pharmacists[J].ZHONGGUO YAOFANG,2024,35(01):95-100. DOI： 10.6039/j.issn.1001-0408.2024.01.17.

摘要

目的

为提升乡镇医疗机构抗菌药物合理使用水平提供参考。

方法

通过县域前置审方中心以抗感染临床药师为主体的团队查找乡镇医疗机构抗菌药物使用中存在的主要问题、进行问题反馈、针对问题组织相关培训、完善前置审方软件的自定义规则、实施自动拦截及药师在线审方等措施，构建以抗感染临床药师为主体的县域医共体抗菌药物使用管理模式。收集该县域医共体15家乡镇医疗机构2022年1－6月（该模式实施前）和2023年1－6月（该模式实施后）的抗菌药物使用数据，并进行比较。

结果

与该模式实施前相比，各乡镇医疗机构门诊患者抗菌药物使用率由实施前的24.97%下降至19.39%，门诊患者抗菌药物注射剂使用率由66.10%下降至46.80%，门诊患者抗菌药物静脉滴注使用率由52.33%下降至40.35%，门诊患者抗菌药物联合使用率由12.70%下降至8.19%，门诊抗菌药物处方点评合理率由55.28%提升至73.93%。实施后，各诊断抗菌药物处方占比与实施前基本一致；按药品解剖学、治疗学及化学分类法分类，少数抗菌药物的用药频度（DDDs）及占比较实施前有所改变，其中林可霉素、庆大霉素等药物的DDDs下降明显；按照AWaRe分级目录分类，各分类抗菌药物DDDs占比与实施前基本一致。

结论

基于县域医共体前置审方中心构建以抗感染临床药师为主体的抗菌药物使用管理模式可有效提升乡镇医疗机构抗菌药物的合理使用水平。

Abstract

OBJECTIVE

To provide reference for improving the rational use of antimicrobial drugs in primary township medical institutions.

METHODS

Based on the county prescription pre-review center， a team led by anti-infective clinical pharmacists constructed the management mode for the use of antimicrobial drugs in county-level medical communities with clinical pharmacists as the main team by finding out the main problems in the use of antimicrobial drugs in primary township medical institutions， providing feedback on the problems， organizing relevant training for the problems， improving the customization rules of the prescription pre-review software， implementing the automatic interception and pharmacist online prescription review and other measures. Data on the use of antimicrobial drugs were collected and compared in the 15 primary township medical institutions between January-June in 2022 （before the implementation of the mode） and January-June in 2023 （after the implementation of the mode）.

RESULTS

Compared with before the implementation of the mode， the utilization rate of antimicrobial drugs in outpatients of primary township medical institutions decreased from 24.97% before the implementation of the mode to 19.39% after the implementation of the mode； the utilization rate of antimicrobial injection in outpatients decreased from 66.10% to 46.80%； the utilization rate of intravenous drip of antimicrobial drugs in outpatients decreased from 52.33% to 40.35%； the rates of combined use of antimicrobial drugs in outpatients decreased from 12.70% to 8.19%； the reasonable rate of antimicrobial prescribing in outpatients increased from 55.28% to 73.93%. After the implementation of the mode， the proportion of antimicrobial prescriptions for each diagnosis was basically the same as before； the defined daily dose system （DDDs） and proportion of a few antimicrobial drugs changed compared with before according to the anatomical therapeutic chemical classification of drugs， among which DDDs of lincomycin， gentamicin and other drugs declined significantly； DDDs of antimicrobial drugs for each classification was basically the same as before according to AWaRe classification.

CONCLUSIONS

The management mode of the use of antimicrobial drugs led by anti-infective clinical pharmacists is constructed in the prescription pre-reviewing center of county-level medical communities， which can effectively improve the rational use of antimicrobial drugs in the primary township medical institutions.

关键词

县域医共体抗菌药物乡镇医疗机构临床药师合理用药

Keywords

antimicrobial drugsprimary township medical institutionsclinical pharmacistsrational drug use

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