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Effects of biapenem on the blood concentration of sodium valproate in patients with severe infections： a retrospective study
更新时间：2025-12-26

    • Effects of biapenem on the blood concentration of sodium valproate in patients with severe infections： a retrospective study

    • “In the field of severe infection treatment, studies have shown that the short-term combination of imipenem has a relatively small effect on the blood concentration of sodium valproate, and can be restored after stopping the drug for 4 to 7 days after long-term combination.”
    • ZHONGGUO YAOFANG   Vol. 36, Issue 24, Pages: 3079-3083(2025)

    • DOI：10.6039/j.issn.1001-0408.2025.24.11    

      CLC： R978.1;R971+.6

    • Received：21 July 2025，

      Revised：2025-12-01，

      Accepted：01 December 2025，

      Published：30 December 2025

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  • CHOU Xiaohua,ZHANG Qian,LIU Zhidong,et al.Effects of biapenem on the blood concentration of sodium valproate in patients with severe infections： a retrospective study[J].ZHONGGUO YAOFANG,2025,36(24):3079-3083. DOI： 10.6039/j.issn.1001-0408.2025.24.11.

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