Study on non-genetic risk factors for antiepileptic drug-induced severe cutaneous adverse reactions in <italic style="font-style: italic">HLA-B</italic>*15：02 negative patients

DENG Mingying; YANG Benjun; FENG Xiaojun; TANG Liqin

doi:10.6039/j.issn.1001-0408.2025.24.13

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Study on non-genetic risk factors for antiepileptic drug-induced severe cutaneous adverse reactions in HLA-B*15：02 negative patients

更新时间：2025-12-26

- Study on non-genetic risk factors for antiepileptic drug-induced severe cutaneous adverse reactions in HLA-B*15：02 negative patients
- “According to the latest research, age ≥ 50 years and use of carbamazepine are independent non genetic risk factors for severe skin adverse reactions related to antiepileptic drugs in HLA-B * 15:02 negative patients.”
- ZHONGGUO YAOFANG Vol. 36, Issue 24, Pages: 3091-3095(2025)
- 作者机构：
  
  中国科学技术大学附属第一医院（安徽省立医院）药学部，合肥　230001
- 作者简介：
- 基金信息：
- DOI：10.6039/j.issn.1001-0408.2025.24.13
  CLC： R971+.6
- Received：29 August 2025，
  
  Revised：2025-10-27，
  
  Accepted：17 November 2025，
  
  Published：30 December 2025
- 稿件说明：
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邓明影,杨本军,冯晓俊,等.HLA-B*15：02阴性患者发生抗癫痫药物相关严重皮肤不良反应的非遗传风险因素研究 ^Δ[J].中国药房,2025,36(24):3091-3095.

DENG Mingying,YANG Benjun,FENG Xiaojun,et al.Study on non-genetic risk factors for antiepileptic drug-induced severe cutaneous adverse reactions in HLA-B*15：02 negative patients[J].ZHONGGUO YAOFANG,2025,36(24):3091-3095.
邓明影,杨本军,冯晓俊,等.HLA-B*15：02阴性患者发生抗癫痫药物相关严重皮肤不良反应的非遗传风险因素研究 ^Δ[J].中国药房,2025,36(24):3091-3095. DOI： 10.6039/j.issn.1001-0408.2025.24.13.

DENG Mingying,YANG Benjun,FENG Xiaojun,et al.Study on non-genetic risk factors for antiepileptic drug-induced severe cutaneous adverse reactions in HLA-B*15：02 negative patients[J].ZHONGGUO YAOFANG,2025,36(24):3091-3095. DOI： 10.6039/j.issn.1001-0408.2025.24.13.

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Study on non-genetic risk factors for antiepileptic drug-induced severe cutaneous adverse reactions in HLA-B*15：02 negative patients

DOI：10.6039/j.issn.1001-0408.2025.24.13