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Study on the apoptosis-inducing effect of esculetin on acute myeloid leukemia HL-60 cells via regulating the AKT/SKP2/MTH1 pathway
更新时间：2026-02-10

    • Study on the apoptosis-inducing effect of esculetin on acute myeloid leukemia HL-60 cells via regulating the AKT/SKP2/MTH1 pathway

    • “The latest research reveals the potential of quercetin (Esc) in the treatment of acute myeloid leukemia (AML). Experts have experimentally verified the mechanism by which Esc regulates the AKT/SKP2/MTH1 pathway to induce apoptosis in AML HL-60 cells, providing new ideas for AML treatment.”
    • ZHONGGUO YAOFANG   Vol. 37, Issue 1, Pages: 36-41(2026)

    • DOI：10.6039/j.issn.1001-0408.2026.01.07    

      CLC： R965

    • Received：17 September 2025，

      Revised：2025-12-17，

      Accepted：19 December 2025，

      Published：15 January 2026

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  • SONG Weihua,CHU Fuying,XIE Wei,et al.Study on the apoptosis-inducing effect of esculetin on acute myeloid leukemia HL-60 cells via regulating the AKT/SKP2/MTH1 pathway[J].ZHONGGUO YAOFANG,2026,37(01):36-41. DOI： 10.6039/j.issn.1001-0408.2026.01.07.

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