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Study on the risk factors and predictive model for acute kidney injury during tacrolimus treatment for pediatric steroid-resistant nephrotic syndrome
更新时间：2026-02-10

    • Study on the risk factors and predictive model for acute kidney injury during tacrolimus treatment for pediatric steroid-resistant nephrotic syndrome

    • “Experts from Xuzhou Children's Hospital have found that baseline renal function impairment, high maximum trough concentration of tacrolimus, CYP3A5 * 3/* 3 genotype, concurrent infections, and hypertension are independent risk factors for acute kidney injury in children with steroid resistant nephrotic syndrome undergoing tacrolimus treatment. A clinical prediction model has been constructed to provide scientific basis for risk stratification management.”
    • ZHONGGUO YAOFANG   Vol. 37, Issue 1, Pages: 66-71(2026)

    • DOI：10.6039/j.issn.1001-0408.2026.01.12    

      CLC： R969.3;R692

    • Received：16 July 2025，

      Revised：2025-11-28，

      Accepted：29 November 2025，

      Published：15 January 2026

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  • LIU Yuqing,ZHU Lei,HAN Zhaohuan,et al.Study on the risk factors and predictive model for acute kidney injury during tacrolimus treatment for pediatric steroid-resistant nephrotic syndrome[J].ZHONGGUO YAOFANG,2026,37(01):66-71. DOI： 10.6039/j.issn.1001-0408.2026.01.12.

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