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Mechanism of Xibining Ⅱ in alleviating cold stimulus pain sensitivity in rats with cold-damp obstruction-type KOA by regulating SETDB2/H3K9me3 signaling axis
更新时间：2026-02-11

    • Mechanism of Xibining Ⅱ in alleviating cold stimulus pain sensitivity in rats with cold-damp obstruction-type KOA by regulating SETDB2/H3K9me3 signaling axis

    • “The Qibi Ning II formula may alleviate inflammation and pain response by activating the SETDB2/H3K9me3 signaling axis, thereby improving the cold stimulation pain sensitivity of cold dampness obstruction type KOA rats. This study provides new ideas and methods for the treatment of cold dampness obstruction type knee osteoarthritis.”
    • ZHONGGUO YAOFANG   Vol. 37, Issue 3, Pages: 324-330(2026)

    • DOI：10.6039/j.issn.1001-0408.2026.03.09    

      CLC： R965

    • Received：26 September 2025，

      Revised：2026-01-07，

      Accepted：09 January 2026，

      Published：15 February 2026

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  • HU Enrui,WEI Yibao,LIU Deren,et al.Mechanism of Xibining Ⅱ in alleviating cold stimulus pain sensitivity in rats with cold-damp obstruction-type KOA by regulating SETDB2/H3K9me3 signaling axis[J].ZHONGGUO YAOFANG,2026,37(03):324-330. DOI： 10.6039/j.issn.1001-0408.2026.03.09.

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