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Improvement effects and mechanism of Achyranthes bidentata total saponins extract on vascular endothelial dysfunction in spontaneously hypertensive rats
更新时间：2026-02-11

    • Improvement effects and mechanism of Achyranthes bidentata total saponins extract on vascular endothelial dysfunction in spontaneously hypertensive rats

    • “Research has found that the extract of total saponins from Achyranthes bidentata can improve endothelial function damage in hypertensive rats, and its mechanism may be related to the regulation of the CYP4A/20-HETE/GPR75 axis, providing new ideas for the treatment of hypertensive vascular injury.”
    • ZHONGGUO YAOFANG   Vol. 37, Issue 3, Pages: 331-337(2026)

    • DOI：10.6039/j.issn.1001-0408.2026.03.10    

      CLC： R965;R285

    • Received：10 September 2025，

      Revised：2026-01-03，

      Accepted：07 January 2026，

      Published：15 February 2026

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  • LIANG Ruifeng,GE Wenjing,KOU Xiaobo,et al.Improvement effects and mechanism of Achyranthes bidentata total saponins extract on vascular endothelial dysfunction in spontaneously hypertensive rats[J].ZHONGGUO YAOFANG,2026,37(03):331-337. DOI： 10.6039/j.issn.1001-0408.2026.03.10.

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HUANG Xiaomei
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Related Institution

Department of Endocrinology,The First Affiliated Hospital of Chongqing Medical University
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