The pharmacy of Yanqing Winter （Paralympic） Olympic Village Polyclinic of 2022 Beijing Winter （Paralympic） Olympic Games will be comprehensively managed from five aspects of man， machine， material， method and environment by adopting the 4M1E management method of quality management tool. In terms of man， constantly enhanced training and daily health monitoring have been insisted； in terms of machine， drug information entry and drug information management have been improved and maintained； in terms of drugs， on the basis of drug management， the management of drugs banned by the World Anti-Doping Agency， class Ⅱ psychotropic drugs and narcotic drugs have been strengthened； in terms of regulations and environment， strict pharmacy workflow and management system have been established， and epidemic prevention closed-loop management requirements have been strictly implemented. From the pre-opening of Yanqing Winter （Paralympic） Olympic Village on January 23， 2022 to the official closing of the Village on March 16， 2022， the clinic pharmacy dispensed a total of 156 prescriptions （105 prescriptions during the Winter Olympic Games， 51 prescriptions during the Winter Paralympic Games）， including 18 prescriptions from the National （Regional） Olympic Committee and the National （Regional） Paralympic Games team doctors， 2 prescriptions containing stimulants that do not need to be exempted from treatment， 1 prescription for narcotics， and 37 prescriptions for athletes （23.7%）. Ibuprofen tablets， Diclofenac diethylamine emulsion， Loratadine tablets and other drugs are widely used. The application of 4M1E management method enables the clinic pharmacy to provide perfect and high-quality pharmaceutical services for large-scale events while doing well in epidemic prevention and control.