OBJECTIVE：To provide reference for establi shing evidence-based pharmaceutical management and assessment system in China. METHODS ：Through literature study and new medical policy interpretation ，the development course of hospital-based health technology assessment （HB-HTA）and its application in pharmaceutical management at home and abroad were traced；the development prospect of HB-HTA in China ’s hospital drug management was discussed. RESULTS & CONCLUSIONS： The HB-HTA makes scientific evaluation on the process of access and use of medical technology ，so as to optimize the allocation of hospital resources and ensure the quality of medical treatment. Foreign countries have used HB-HTA to assist the decision-making of hospitals. China ’s HB-HTA is still in its initial stage and lags behind the international leading level. As effective means for cost control and quality improvement ，HB-HTA should be applied in drug management and assessment system as soon as possible；it is necessary to explore suitable drug assessment mode （i.g. ambassaclor mode ，Mini-HTA mode ，internal committee mode，HB-HTA unit mode ），strengthen HTA personnel training ，establish HTA methodology （such as Mini-HTA mode assessment tool included outline ，general information ，general methods ，multi-structure evaluation results ，discussion，conclusions and recommendations），pay more attention to it and promote the transformation of achievements.