OBJECTIVE： To provide theoretical basis and data support for community extended prescription management and pharmaceutical care. METHODS： Data of all patients using extended prescription from 2017 to 2018 were derived from the health information system database of Jinshan district of Shanghai and 11 streets towns under its jurisdiction. Retrospective survey was used to analyze the basic medical information of extended prescription patients and the compliance with extended prescription execution （insisting on dispensing drugs through extended prescription within 2 years）， and the factors affecting compliance were analyzed. RESULTS： From 2017 to 2018， there were 4 835 patients with Jinshan district extended prescription， with prescribing rate （number of extended prescriptions/number of prescriptions） of 2.08％， mainly patients over 60 years old （4 038 cases， 83.51％） and patients with common chronic diseases [4 793 casetimes， 83.18％ （4 793/5 763）]； there was statistical significance in the prescribing rate of extended prescription among different streets and towns （P＜0.05）. The overall compliance rate of extended prescription patients in Jinshan district was 81.62％ （62.02％-88.84％）. There was no significant difference in compliance rate of extended prescription execution between male and female patients （P＞0.05）. Age， type of disease and types of extended prescription drugs had influence on compliance rate of extended prescription patients. Compliance rate of extended prescription in patients under 40 years of age or hypertension and chronic airway disease or those who were given one kind of drug was lower than other patients in same group （P＜0.05）. CONCLUSIONS： Big data can be used for monitoring the compliance of extended prescription in the future. At the same time， pharmacists participating in family doctor team formulate relevant guidance and education for poor compliance group so as to improve the rationality and effectiveness of extended prescription for patients.