OBJECTIVE： To analyze the reliability and validity of Chinese version of MMAS-8 in evaluating the medication compliance of patients with chronic cardiovascular diseases， and to evaluate the effects of medication reconciliation on medication compliance. METHODS： Totally 97 patients with chronic cardiovascular diseases were selected as observation group. The reliability and validity of the questionnaire were analyzed and medication reconciliation was carried out. Totally 91 patients with chronic cardiovascular diseases were selected as control group， and given routine medical services. 8-item Morisk Medication Compliance Scale used to evaluate the drug compliance of the two groups at different time points. RESULTS： The F-test and t-test of the average score of 8 items in 27％ of questionnaire score ranking head and tail of the two extreme groups had statistical significance （P＜0.001）. Correlation coefficient between the 8 items and the total scores was higher than 0.400， and the 8 items were significantly correlated with total scores （P＜0.001）. Internal consistency reliability coefficient was 0.763； the structure validity KMO value was 0.742； the Bartlett’s spherical test value was 266.007； factor analysis method was adopted to extract 2 common factors， and explained total variance was 58.907％. Compared with control group， medication compliance of observation group was improved significantly at the first week after discharge and one month after discharge （P＜0.05）. CONCLUSIONS： The Chinese version of MMAS-8 has good reliability and validity in evaluating drug compliance of patients with chronic cardiovascular disease； medication reconstitution service can improve medication compliance of patients.