OBJECTIVE： To provide reference for the construction of collaborative model between pharmacists and physicians during diagnosis and treatment in China. METHODS： Four representative collaborative models between pharmacists and physicians were selected， namely， “collaborative working relationship”， “conceptual model of general practitioner and community pharmacist collaboration”， “community pharmacist attitudes towards collaboration with general practitioners/general practitioner attitudes towards collaboration with community pharmacists” and “physician-community pharmacists collaboration Meta-model”. The main points and characteristics of each model were compared and analyzed so as to put forward the framework of pharmacists and physicians collaborative model in China. RESULTS & CONCLUSIONS： Collaborative working relationship model divided the level of cooperation into five stages and considered that the effects of the factors in different stages were different. Conceptual model of general practitioner and community pharmacist collaboration divided the level of cooperation into three stages and considered that the features of the factors in different stages were different. Community pharmacist attitudes towards collaboration with general practitioners/general practitioner attitudes towards collaboration with community pharmacists chose community pharmacist or general practitioner as the starting point and found the correlation between some factors. Physician-community pharmacists collaboration Meta-model selected important factors based on the summary. Using the above models for reference， the author constructs the framework of collaborative model between pharmacists and physicians consisting of five collaboration levels， which were demand germination period， value identification period， relation run-in period， pattern strengthening period and relation formation period， and three major influenctial factors as individual characteristics， employment environment characteristics and interaction characteristics.