OBJECTIVE： To establish a method for the content determination of 8 metal elements in Propylgaclate and sodium chloride injection. METHODS： Microwave digestion-inductively coupled plasma mass spectrometry（ICP-MS） was adopted.  Radiofrequency power was 1 530 W； cooling temperature was 4 ℃； collision gas was He gas； carrier gas was argon； flow rate of carrier gas was 1.08 L/min； integration time was 0.3 s； plasma gas flow rate was 15 L/min； the vacuum degree of quadrupole was 3.04×10－4 Pa； sampling cone aperture was 1.0 mm； interception cone aperture was 0.4 mm； the speed of sampling was 0.3 rps； data collection was repeated for 3 times. The microwave digestion power is 1 600 W， and the heating process is heated to 160 ℃ at room temperature for 30 min， and maintained at 5 min， and then heated to 190 ℃ at a temperature of 5 ℃/min and maintained 45 min.  RESULTS： The linear range of Mg and Al were 1-250 ng/mL； the linear range of Cr， Mn， Fe， Cu， Zn， Cd were 1-100 ng/mL（all r≥0.999 0）. The limits of detection were 0.063 6-1.785 0 ng/mL. RSDs of precision， stability and reproducibility tests were all lower than 4％. The recoveries were 89.65％-105.60％（RSD were 1.57％-3.98％，n＝9）. RSDs of durablity were all lower than 12％. CONCLUSIONS： The method is simple， accurate， precise， stable， reproducible and durable. It can be used for content determination of 8 metal elements in Propylgaclate and sodium chloride injection.