OBJECTIVE： To provide reference for understanding the significance of drug proportion control deeply and future direction of hospital reform. METHODS： The data were collected from the relevant statistical reports of our hospital in August 2016， June and August 2017. The data were analyzed statistically and compared in respects of drug proportion， income， medical cost， ratio of essential medicine types， prescription amount （outpatient and emergency department）， utilization rate and utilization density （AUD） of antibiotics in whole hospital， outpatient and emergency department， inpatient department. RESULTS： The drug proportion of our hospital was decreased significantly in Aug. 2017 （after drug price reform）， which fell by 13.35％ from the previous month and 17.58％ year-on-year. Hospital revenues were on the rise， which increased by 6.92％ from the previous month and 11.45％ year-on-year. Outpatient and emergency income was decreased slightly from the previous month （by 2.73％）. Inpatient income was increased significantly from the previous month （by 9.76％）. Per capita medical cost in outpatient and emergency department were increased， which increased by 4.01％ from the previous month and 9.62％ year-on-year； per capita medical cost of inpatients were declined， which fell by 0.91％ from the previous month and 3.11％ year-on-year. The ratio of essential medicine types in the whole hospital was decreased slightly from the previous month but increased by 17.79％ year-on-year. Drug amount of outpatient and emergency prescriptions was decreased by 11.34％ from the previous month and prescription amount decreased by 9.16％ year-on-year. The utilization rate of antibiotics in the whole hospital was decreased by 8.10％ from the previous month； AUD was decreased by 3.88％ from the previous month and 13.88％ year-on-year.  CONCLUSIONS： After drug price reform， drug proportion of our hospital is effectively controlled， which has a positive influence on the operation of medical service system and patient medical cost. At the same time， some problems that need to be solved are also exposed， such as increase in per capita medical costs and the decrease in the number of outpatient and emergency patients. So， drug proportion control is only the first step in deepening hospital reform， and the follow-up motivation still needs to be provided continuously through strengthening rational drug use.