OBJECTIVE: To improve accuracy rate of automatic tablet dispensing machine in the inpatient pharmacy. METHODS: The risks and corresponding control methods in the use of automatic tablet dispensing machine in inpatient pharmacy of our hospital were summarized and analyzed. RESULTS & CONCLUSIONS: Effective risk control was carried out in the inpatient pharmacy of our hospital in the respects of drug preparation, drug stripping, drug supplement and medical order examination. At the same time, it also strengthened the standardized management of unpacked medicines, standardized the labeling of medicine boxes, regularly maintained the automatic tablet dispensing machine, established related system and standard operation procedure and standardized staff training and examination system, which reduced the occurrence of errors and ensured the safety of patients’ medication.