OBJECTIVE: To optimize extraction technology of Shenqi fukang granules. METHODS: Single factor method was used to investigate water multiple at first time using water absorption as index, soaking time using yield of dry extract as index. Based on single factor test, by weighted comprehensive scoring method, using the yield of dry extract and the content of 75% ethanol extraction as indexes, extraction time, water multiple and extraction times as factors, L9(34) orthogonal test was used to optimize water extraction technology of Shenqi fukang granules. Validation test was conducted. RESULTS: The optimal water extraction technology included 8-fold water (L/kg), extracting for 3 times, 1 h each time. CONCLUSIONS: The optimized extraction technology is stable and controllable in quality, and can provide reference for industrial production of Shenqi fukang granules.
关键词
参芪妇康颗粒提取工艺正交试验干膏得率乙醇浸出物含量
Keywords
Shenqi fukang granulesExtraction technologyOrthogonal testYield of drug extractContent of ethanol extract