OBJECTIVE： To complete standardized management and follow-up for the cancer pain and chronic pain patients in outpatient department. METHODS： Information management platform was designed and established for cancer pain and chronic pain patients in outpatient department， including  information entry， information inquiry， prompt for drug dispensing in advance， file unified management and regular scanning and removing excess medical records. The procedure of prescribing narcotic drugs for first visiting， subsequent visiting and follow-up patients was introduced. File management and prescription rationality before and after the establishment of information platform were compared. The adoption of pharmacist’s recommendation after the establishment of information platform were counted. RESULTS： Compared with before the establishment of information platform， the ratio of problematic profiles decreased from 42.96％ to 7.06％（P＜0.05）； the ratio of irrational prescription decreased from 4.39％ to 1.19％（P＜0.05）. Pharmacists provided a total of 1 542 recommendations for the patients with poor pain control and ADR. The adoption rate of the pharmaceutical recommendations was 63.62％. CONCLUSIONS： The cancer pain and chronic pain information management platform can manage the outpatients’ profile effectively and improve the rationality of the prescription. Meanwhile， the pharmacists have played an important role in the pain treatment for outpatients.