OBJECTIVE： To promote the realization of intelligent management for narcotic and first type psychotropic drugs （narcotic and psychotropic drugs for short） in hospital. METHODS： With the aid of fingerprint identification technology and hardware devices such as intelligent storage cabinet， intelligent management for narcotic and psychotropic drugs were designed and developed in our hospital， including prescription dispensing， cardinal drug supplement， empty bottle recycling， changing shifts， etc. The effects of the system were evaluated 30 d before and after the implementation of the system through comparing related indexes. RESULTS： The application of intelligent management system for narcotic and psychotropic drugs realized intelligent dispensing of narcotic and psychotropic drugs， automatic checking during cardinal drug supplement， automatic information record during empty bottle recycling， automatic record during changing shifts， intelligent and information management on “five specific management” for narcotic and psychotropic drugs. Compared with before the implementation of the system， the duration of daily changing shifts was shortened from （13.62±0.40） min to （8.67±0.33） min， shortening by 4.95 min in average （n＝30）. The time of prescription dispensing was shortened from （30.36±0.48） min to （10.56±0.46） min， shortening by 19.80 min（n＝30）. The collecting time of cardinal drug supplement was shortened from （12.72±0.97） min to （0.13±0.03） min， shortening by 12.59 min （n＝30）. No drug dispensing error was found after the implementation of the system. CONCLUSIONS： The system is stable and convenient， which promotes that intelligent management for narcotic and psychotropic drugs is in line with the requirements of “five specific management”. It also realizes intelligent and information operation， improves work efficiency and error prevention ability.