OBJECTIVE： To evaluate the effect and role of Pharmaceutical Care Network Europe （PCNE） classification system  （8.0 edition） on drug-related problems （DRPs） in respiration department. METHODS： Clinical pharmacists provided pharmaceutical care for DRPs in a patient with acute exacerbation of chronic obstructive pulmonary disease of respiration department by using PCNE classification system （8.0 edition）. Type， cause， intervention measure， intervention acceptability and state of DRPs were analyzed. RESULTS： PCNE classification system （8.0 edition） mainly included 5 aspects as problems， reasons， plan intervention， the acceptance of intervention plan， the situation of DRPs. Clinical pharmacists confirmed the type of DRPs， with the help of the system and solved two items of DRPs. Physicians accepted intervention and fully implemented it. CONCLUSIONS： Clinical pharmacists can provide standardardized pharmaceutical care systematically， discover and solve DRPs in time through PCNE classification system （8.0 edition） so as to guarantee safe， effective and reasonable drug use.