OBJECTIVE： To establish a method for simultaneous determination of gallic acid， magnoflorine， ellagic acid， jatrorrhizine hydrochloride， palmatine hydrochloride， berberine hydrochloride and curcumin in Siwei jianghuang decoction powder. METHODS： HPLC method was adopted. The determination was performed on Capcell Pak C18-MG Ⅱ column with mobile phase consisted of acetonitrile-0.1％ phosphoric acid （gradient elution） at the flow rate of 0.8 mL/min. The detection wavelengths were 270 nm （0-60 min， gallic acid， magnoflorine， ellagic acid， jatrorrhizine hydrochloride， palmatine hydrochloride， berberine hydrochloride） and 428 nm （60-70 min， curcumin）. The column temperature was set at 30 ℃， and sample size was 10 μL. RESULTS： The linear ranges of gallic acid， magnoflorine， ellagic acid， jatrorrhizine hydrochloride， palmatine hydrochloride， berberine hydrochloride and curcumin were 0.249 6-1.497 6， 0.284 0-1.704 0， 0.075 6-0.453 6， 0.015 9-0.095 9， 0.023 6-0.141 6， 0.098 2-0.589 0 and 0.060 4-0.362 4 μg （r≥0.999 8）. The limits of detection were 6.24， 4.73， 7.56， 2.36， 3.20， 6.54， 6.04 ng， and the limits of quantitation were 17.47， 16.08， 20.86， 7.31， 10.24， 19.62， 19.32 ng， respectively. RSDs of precision， stability （12 h）， reproducibility tests were lower than 2.0％ （n＝6）. The recoveries were 95.45％-103.47％ （RSD＝0.86％-1.98％， n＝9）. CONCLUSIONS： Established method is simple， accurate， reliable and suitable for simultaneous determination of 7 components such as gallic acid in Siwei jianghuang decoction powder.