OBJECTIVE： To improve the quality standard of Compound shougong powder. METHODS： Gekko japonicas and Armeniaca mume were identified by microscopic identification. TLC method was adopted to identify processed Fallopia multiflora qualitatively. The content of 2，3，5，4-tetrahydroxystilbene-2-O-β-D-glucoside （stilbene glycoside） was determined by HPLC. The determination was performed on Agilent Zorbax Eclipse XDB-C18 column with mobile phase consisted of acetonitrile-water （19 ∶ 81，V/V） at the flow rate of 1.0 mL/min. The detection wavelength was set at 320 nm， and column temperature was 25 ℃. The sample size was 10 μL. RESULTS： Microscopic characteristics of skin fragments and scales of G. japonicas and the pollen grains of A. mume were significant without interference from negative control. TLC spots of F. multiflora were clear and well-separated without interference from negative control. The linear range of stilbene glucoside were 23-368 μg/mL （r＝0.999 9）. RSDs of precision， stability and reproducibility tests were all lower than 1.0％. The recoveries ranged 98.69％-101.61％ （RSD＝0.94％，n＝9）. CONCLUSIONS： Improved standard can effectively control the quality of Compound shougong powder.