OBJECTIVE： To establish a method for simultaneous determination of 4 residual organic solvents such as ethanol， dichloromethane， isopropanol and ethyl acetate in lacidipine raw material. METHODS： GC method was adopted. The determination was performed on DB-624 capillary column at the rate of 2.0 mL/min using nitrogen gas as carrier and FID as the detector by temperature programming. The temperature of detector was set at 250 ℃. Carries gas was nitrogen. The split ratio was 10 ∶ 1. The sample size was 10 μL. RESULTS： The linear ranges of ethanol， dichloromethane， isopropanol and ethyl acetate were 0.259 5-2.076 mg/mL （r＝0.999 6）， 0.055 3-0.316 mg/mL （r＝0.999 2）， 0.342 3-1.956 mg/mL （r＝0.999 5）， 0.370 6-2.118 mg/mL（r＝0.999 4）， respectively. The limits of quantification were 2.96， 2.24， 4.4， 4.44 μg/mL， and the detection limits were 0.887，0.672，1.3，1.32 μg/mL， respectively. RSDs of precision， stability and reproducibility tests were all lower than 4.0％. The recoveries were 95.00％-101.17％（RSD＝2.19％，n＝9）， 96.22％-104.53％（RSD＝3.27％，n＝9）， 96.20％-104.90％（RSD＝2.41％，n＝9）， 95.60％-104.48％（RSD＝2.85％，n＝9）. CONCLUSIONS： The method is simple， sensitive and reliable， and is suitable for simultaneous determination of 4 residual organic solvents in lacidipine raw material.