OBJECTIVE： To investigate the effects of different drying methods on contents of active ingredients in leaves of Eucommia ulmoides， and provide reference for establishing its drying methods after habitat harvesting. METHODS： Different drying methods [natural drying in the shade for 72 h， natural drying in the sunlight for 36 h， drying beside or over a fire （60 ℃ 6 h， 80 ℃ 2 h， 100 ℃ 1 h， 120 ℃ 0.5 h）， microwave vacuum freeze drying for 12 h， vacuum freeze drying for 12 h] were used for processing. HPLC was conducted to determine the contents of aucubin， geniposidic acid， chlorogenic acid and geniposide in samples and compare with the untreated fresh products. RESULTS： Contents of 4 ingredients in samples after the 2 freeze drying were close to these in fresh samples， which were higher than samples after other drying. CONCLUSIONS： Drying methods show significant effects on the effective ingredients in leaves of E. ulmoides. Compared with natural drying in the shade and natural drying sunlight and drying beside or over a fire， microwave vacuum freeze drying and vacuum freeze drying can make better retention of the active ingredients in fresh leaves of E. ulmoides.