OBJECTIVE： To establish a method for the simultaneous determination of 7 components in Tanreqing capsules. METHODS： HPLC method was adopted. The determination was performed on Ultimate XB C18 column with mobile phase consisted of acetonitrile-0.2％ formic acid （gradient elution） at a flow rate of 0.8 mL/min. The detection wavelength was set at 325 nm， and column temperature was 35 ℃. The sample size was 10 μL. RESULTS： The linear ranges of chlorogenic acid， isoforsythiaside A， forsythiaside A， isochlorogenic acid B， isochlorogenic acid A， isochlorogenic acid C and baicalin were 0.025-0.5 μg（r＝0.999 6）， 0.025-0.5 μg （r＝0.999 7），0.050-1.0 μg （r＝0.999 9），0.025-0.5 μg（（r＝0.999 7）， 0.025-0.5 μg （（r＝0.999 6）， 0.025-0.5 μg （r＝0.999 6）， 0.750-1.5 μg（r＝0.999 9）， respectively. The limit of quantitation was no more than 1.5 ng， and the limit of detection was 0.5 ng. RSDs of precision， stability and reproducibility tests were all lower than 3.0％. The recoveries were 95.28％-106.30％ （RSD ranged 0.97％-2.14％，n＝9）. CONCLUSIONS： The method is simple， precise， stable and reproducible， and can be used for simultaneous determination of 7 components in Tanreqing capsules.