OBJECTIVE： To develop a method for simultaneous determination of geniposide， baicalin， aloe-emodin， rhein， emodin， chrysophanol and physcion in Zhizi jinhua dispersible tablets. METHODS： HPLC method was adopted. The determination was performed on Dimonsil C18 column with mobile phase consisted of methanol-0.05％ phosphoric acid （gradient elution） at the flow rate of 0.8 mL/min. The detection wavelength was set at 254 nm， and the column temperature was 25 ℃. The sample size was 20 μL. RESULTS： The linear ranges of geniposide， baicalin， aloe-emodin， rhein， emodin， chrysophanol and physcion were 0.032 3-0.323 μg（r＝0.999 8），0.137 4-1.374 μg（r＝0.999 9），0.003 72-0.037 2 μg（r＝0.999 7）， 0.006 9-0.069 μg（r＝0.999 5）， 0.003 32-0.033 2 μg（r＝0.999 7）， 0.008 64-0.086 4 μg（r＝0.999 7） and 0.001 22-0.012 2 μg（r＝0.999 5）， respectively. The limits of quantitation were 0.032 1，0.137 4， 0.003 72， 0.006 7， 0.003 30， 0.008 64， 0.001 22 μg， respectively. The limits of detection were 0.009 5， 0.004 1， 0.001 2， 0.002 0， 0.001 0， 0.002 6， 0.000 3 μg， respectively. RSDs of precision， stability and reproducibility tests were all lower than 3％. The average recoveries were 96.54％-99.52％（RSD＝1.17％，n＝6），97.23％-101.23％ （RSD＝1.36％，n＝6），97.22％-101.25％（RSD＝1.83％，n＝6），97.32％-100.23％（RSD＝1.09％，n＝6）， 97.99％-102.71％（RSD＝1.73％， n＝6）， 96.99％-100.23％（RSD＝1.21％，n＝6）， 96.99％-103.01％（RSD＝2.31％，n＝6）， respectively. CONCLUSIONS： The methods is simple and reproducible. It can be used for the content determination of 7 components in Zhizi jinhua dispersible tablets.