OBJECTIVE： To establish quality standard for Zhuang medicine Homalocladium platycladum. METHODS： TLC method was used for qualitative identification. HPLC method was used to determine the content of quercetrin in samples： Agilent Zorbax SB-C18 column， mobile phase consisted of acetonitrile-0.1％ acetic acid （20 ∶ 80，V/V）， flow rate of 1.0 mL/min， detection wavelength of 360 nm， column temperature of 30 ℃，injection volume of 10 μL. The contents of moisture， total ash and extract in samples were determined. referring to Chinese Pharmacopiea（2015 edition）. RESULTS： TLC spots of H. platycladum were clear and well-separated without interference from negative control. The linear range of quercetin were 0.023-0.46 mg/mL（r＝0.999 1）. RSDs of precision， stability and repeatability tests were all lower than 2.0％. The average recoveries were 98.01％-103.05％ （RSD＝1.71％，n＝6）. The contents of moisture， total ash，extract and quercetrin in samples were 6.39％-9.78％， 2.82％-8.07％， 0.02％-0.27％， 14.14％-28.45％， 0.09％-0.50％ respectively.  CONCLUSIONS： Established trial can be used for quality control of Zhuang medicine H. platycladum.