OBJECTIVE： To improve the effectiveness of experimental teaching and independent hands-on ability of the students. METHODS： Combined with teaching characteristics of newly established universities， the characteristics of instrumental analytical experiment teaching and the characteristics of pharmaceutical students， “flipped classroom” and project modular design were applied to instrumental analytical experiment teaching together. The instrumental analytical experiment teaching was expounded and integrated in respects of curriculum content design， teaching implementation and curriculum assessment. RESULTS&CONCLUSIONS： The students achieve the knowledge learning after classroom， and complete the knowledge absorption and mastering in class with the help of video and audio information. It also improved independent learning ability of the students， strengthened the ability of interactive learning and cooperative learing between teachers and students and among students. It is feasible to apply the “flipped classroom” and the experimental project modular design in the instrument analytical chemistry experiment teaching reform. This method also can provide some references for the reform of instrument analytical chemistry experiment teaching.