OBJECTIVE： To observe therapeutic efficacy and safety of Shensong yangxin capsule combined with low-dose amiodarone in the treatment of ventricular tachyarrhythmia. METHODS： In retrospective analysis， 106 patients with ventricular tachyarrhythmia were divided into control group and observation with 53 cases in each group according to drug use. Based on conventional treatment， control group was additionally given Amiodarone tablet （first week：0.2 g each time，3 times a day；second week：0.2 g each time， 2 times a day； third week to the end of the treatment：0.2 g each time， 1 times a day），orally. Observation group was given Amiodarone tablet  （first week： 0.2 g each time， twice a day； second week to the end of the treatment：0.2 g each time， 1 times daily），orally +Shensong yangxin capsule 1.6 g， 3 times a day， orally. Both groups were treated for 8 weeks. Clinical efficacy， blood pressure， heart rate and electrocardiogram （PR period and QT period）and the cardiac cardioversion time were compared between 2 groups， and the occurrence of ADR was also recorded during treatment. RESULTS： After treatment， total response rate of observation group （94.34％） was higher than that of control group （81.13％）， the incidence of ADR was lower than that of control group （3.77％ vs. 13.21％） and the cardiac cardioversion time was shorter than that of control group，with statistical significance （P＜0.05）. Before treatment， there was no statistical significance in heart rate between 2 groups； after treatment， heart rate of 2 groups were significantly lower than before， and observation group was significantly lower than control group，with statistical significance （P＜0.05）. There were no statistical significance in blood pressure、PR period and QT period between 2 groups before and after treatment （P＞0.05）. CONCLUSIONS： Based on conventional treatment， Shensong yangxin capsule combined with low-dose amiodarone have good therapeutic efficacy with rapid response for ventricular arrhythmia，it can significantly improve the heart rate of the patients， and the effect is faster with good safety .