OBJECTIVE: To provide reference for rational use of cancer pain narcotic drugs in our hospital. METHODS: The amount of narcotic drugs in our hospital was analyzed statistically during second quarter of 2012 to second quarter of 2015. RESULTS: 12 specifications and 4 dosage forms of narcotic drugs were involved in our hospital during second quarter of 2012 to second quarter of 2015. Total amount of narcotic drugs was in an increasing tendency. Oxycodone hydrochloride sustained-release tablet was the largest quantity of narcotic drug used and grew fastest. The amount of surgical drugs kept stable, while total amount of oral preparation increased significantly, in particular, a significant increase in Morphine tablets. CONCLUSIONS: The application of narcotic drugs in our hospital is basically reasonable. The preferred oral principle has been implemented, and treatment of cancer pain is more standardized.