OBJECTIVE： To investigate the characteristics and general rule of ADR induced by Ginkgo leaf extract and dipyridamole injection， and to provide reference for clinical rational drug use. METHODS： Using “Ginkgo leaf extract and dipyridamole injection” “ADR” as subject， the journal articles were retrieved from CJFD during Jan. 1st， 2005-Jun. 28th， 2016， and then analyzed statistically in respects of gender， age， primary disease， allergic disease， drug use， occurrence time of ADR， organs/systems involved and clinical manifestations. RESULTS： A total of 14 valid articles had been collected， involving 727 patients in total. Meanwhile， female was more than male （57.63％ vs. 42.37％） and most of them aged more than 50 years； primary diseases were mainly thromboembolic disease and coronary heart disease； most of ADR happened within 30 min after medication （268 cases， 36.86％）. Organs/systems involved in ADR were mainly nervous system （254 cases， 28.60％）， followed by skin and its appendants （228 cases， 25.68％）， digestive system （187 cases， 21.06％）； severe ADR could cause anaphylactic shock. There were 18 cases of new severe ADR （2.48％）； all ADR cases were recovered， and no death occurred. CONCLUSIONS： It is suggested to strictly control indications， differential diagnosis and treatment， rational drug use， close monitoring through the whole process， maintain a high level of awareness to ADR.