OBJECTIVE： To evaluate the stability of 12 kinds of submicro emulsion in market， and screen the test method for the stability. METHODS： 12 kinds of submicro emulsion in market were selected， high pressure sterilization （121 ℃， 30 min）， high speed centrifugation （4 000 r/min， 15 min）， accelerated test [placing 6 months under temperature of （40±2） ℃， relative humidity of （75±5）％] were conducted to investigate the pH， particle size and other indexes， and SPSS 22.0 was used to analyze the distribution variance and chi-square test， and investigate the correlation of 3 evaluation methods. RESULTS： In terms of stability investigation， the pH value of 12 kinds of submicro emulsion decreased to some extent after accelerated test， average particle size of 6 kinds of submicro emulsion samples were greater than 300 nm， the variance of the particle size distribution of 9 kinds appeared in 0.05-0.15， the chi-square test results of 8 kinds distributed below 1. The average particle size of 4 kinds of submicro emulsions changed more than 10 nm after accelerated test. In terms of stability test method， Pearson chi-square progressive significance of high pressure sterilization and accelerated test was 0.665， which was higher than 0.05， indicating there was no correlation （no significance）， the stability results of high pressure sterilization can not represent the results of accelerated test； that of high speed centrifugation and accelerated test was 0.004， which was lower than 0.05， indicating stability results between high speed centrifugation and accelerated test results were significantly correlated. CONCLUSIONS： The submicro emulsion in market can meet the requirements of stability. To a certain extent， high speed centrifugation can replace the acceleration test.