OBJECTIVE： To investigate the clinical pharmacy status of partial third-level first class hospitals in Guangxi Yulin， and provide reference for promoting its development in medical and health institutions in domestic development cities and regions. METHODS： Questionnaire was combined with interviews to investigate the medical staff （part）， clinical pharmacists and directors in pharmacy department in 4 third-level first class hospitals in Yulin， and the data was statistically analyzed. RESULTS： Totally 242 questionnaires were sent out for the medical staff， 238 were effectively received， with effective recovery of 98.35％； 15 for clinical pharmacists， 15 were effectively received， with effective rate of 100％； the interview for directors in pharmacy department of 4 hospitals was done well. The 4 surveyed hospitals all had clinical pharmacists， while only 2 had met the requirement on amount of clinical pharmacists； the clinical pharmacists were all with the bachelor degree or above， no senior titles. In terms of cognitive functions of clinical pharmacists， the 5 items， including dispensing， pharmacy intravenous admixture services， hospital preparation， hospital drug supply and drug quality testing， were considered to be the functions of clinical pharmacist by more than 50％ surveyed medical staff， while only less than 20％ clinical pharmacists agreed with this view. In terms of individualized administration capacity， only one hospital can carry out vancomycin for therapeutic drug monitoring known from the interview； 58.82％ surveyed medical staff were general satisfied and very satisfied to the work of clinical pharmacists. In terms of obstacles to the development of clinical pharmacy， surveyed clinical pharmacists considered that difficulties in clinical work included insufficient capacity （93.33％） and the misunderstanding of doctors and patients （were both 60.00％）； in the medical information consultation the most prominent difficulty was information query resource constraints （100％）. CONCLUSIONS： The clinical pharmacy in the third-level first class hospital of Guangxi Yulin can complete their task almost in the work， and the implementation of clinical pharmacist is good， however， there is still a great space for development in the quantity and quality of clinical pharmacists， the cognition of medical personnel on clinical pharmacists， hardware facilities， etc.