OBJECTIVE： To improve automatic outpatient pharmacy drug delivery system in our hospital， and to promote the efficiency of automatic drug delivery. METHODS： The outpatient pharmacy automation system of our hospital was introduced in terms of main structure， working process and application. The work efficiency， safety and error were compared between automatic drug delivery mode and manual drug delivery mode. Drug delivery machine was improved to increase the rate of drug delivery. RESULTS： The outpatient pharmacy automation system of our hospital included 2 boxed drug delivery machine and 1 drug dispensing machine， etc. Compared with manual drug delivery mode， automatic drug delivery mode improved drug delivery efficiency， health security and use security， and reduced drug delivery error. Through adjusting the time setting and step of drug delivery of gearing in drug delivery machine， idle time of transmission equipment was utilized effectively， and the quantity of delivered prescriptions was increased， increasing from 220 to 320 each hour. CONCLUSIONS： The reasonable improvement of outpatient pharmacy automation system makes outpatient pharmacy automation system play a bigger role， and further optimize resources.