OBJECTIVE: To investigate the application of antiplatelet drugs and statins for patients with hypertension and diabetes in Chongqing, and provide reference for promoting the rational use of the 2 drugs for the patients. METHODS: Questionnaires were conducted for the patients with hypertension and diabetes in 4 hospitals of Chongqing from Sept. 2012 to Sept. 2015, and the related data was statistically analyzed. RESULTS: Totally 1 800 questionnaires were sent out, 1 800 were effective received, with effective recovery of 100%. In the 1 800 patients, only 28.9% patients were taking antiplatelet drugs, in which, 33.7% patients with antiplatelet drugs showed shorter time of treatment than the history of hypertension and diabetes, 21.5% patients orally received aspirin 100 mg/d+clopidogrel 75 mg/d dual antiplatelet treatment; the main reason without taking antiplatelet therapy was that 39.2% patients thought it was not necessary to take medicine, 23.0% patients feared side effects and 17.5% was not aware of using the drug. 45.7% patients were taking statins, in which, 29.3% patients with antiplatelet drugs showed shorter time of treatment than the history of hypertension and diabetes; simvastatin (20-39 mg/d) and atorvastatin (10-19 mg/d) were the most commonly used dose, accounting for 24.4% and 25.3% of the total number of statins, respectively; the main reason without taking statins was that 33.2% patients thought it was not necessary to take medicine, 20.9% patients thought it was too expensive, and 15.8% was not aware of using the drug. CONCLUSIONS: The antiplatelet drugs and statins are still underused in hypertension and diabetes patients in the 4 hospitals of Chongqing.