OBJECTIVE： To investigate the effects of perioperative application of Eucalyptol， limonene and pinene （ELP） enteric soft capsules on therapeutic efficacy and prognosis in children after grommet insertion of chronic secretory otitis media. METHODS： 92 cases （145 ears） of chronic secretory otitis media were divided into 2 groups by random number table method， including 46 cases in observation group （68 ears） and 46 cases in control group （77 ears）. Both groups received grommet insertion under general anesthesia by otomicroscope. Control group was not given any drugs； observation group was given ELP enteric soft capsules 1.2 g， bid， from 3 d before operation to 5 d after operation. Subjective therapeutic efficacy and pure tone audiometry of 2 groups were observed 3 days， 5 days， 2 weeks， 1 month and 3 months after surgery as well as acoustic impedance monitoring in children with tube withdrawal from ear 1 month and 3 months after surgery. RESULTS： The total effective rates of observation group 3 days， 5 days， 2 weeks， 1 month and 3 months after surgery were 72.06％， 82.35％， 85.29％， 89.70％ and 95.59％； those of control group were 59.74％， 66.23％， 80.52％， 87.01％ and 92.21％， with statistical significance （P＜0.05）. The pure tone audiometry score of observation group 3 days， 5 days， 2 weeks， 1 month and 3 months after surgery were significantly lower than those of control group， with statistical significance （P＜0.05）. Therapeutic effective rates of acoustic impedance monitoring in children with tube withdrawal from ear 1 month and 3 months after surgery were 77.78％ and 90.48％ in observation group， which were significantly higher than 61.54％ and 81.48％ in control group， with statistical significance （P＜0.05）. CONCLUSIONS： The perioperative application of ELP enteric soft capsules can significantly improve function recovery and hearing level in children after grommet insertion of chronic secretory otitis media.