OBJECTIVE： To establish the quality standard for Solanum tuberdsm. METHODS： The microscopic characteristics were detected； TLC was used for qualitative identification； moisture， ash， heavy metals and the amount of extract were determined； HPLC was conducted for content determination of oxidized cyanidin： the column was Alltima C18 with mobile phase of acetonitrile-0.1％ trifluoroacetic acid （80 ∶ 20，V/V） at a flow rate of 1.0 ml/min， detection wavelength was 538 nm， column temperature was 30℃. RESULTS： It showed clear microscopic identification map. S. tuberdsm TLC had clear spots and well separated. The water content was 8.5％-11.0％； total ash was 2.0％-2.9％； Pb was lower than 5 ppm and alcohol-soluble extracts was 15.6％-22.3％. The linear range of oxidized cyanidin was 0.043-0.215 μg （r＝0.999 8）； RSDs of precision，stability and reproducibility tests were lower than 2.0％；recovery was 95.50％-99.65％（RSD＝1.35％，n＝9）. CONCLUSIONS： The established method can be used for the quality control of S. tuberdsm.