OBJECTIVE： To establish the quality standard of Qinglian ningxin capsule. METHODS： TLC was adopted for the qualitative identification of Coptis chinensis and Artemisia carvifolia. HPLC was used for the content determination of artemisinin： column was Diamonsil C18 with mobile phase of methanol-phosphate buffer solution （45 ∶ 55，V/V） at a flow rate of 1.0 ml/min， detection wavelength was 260 nm， column temperature was 30 ℃，and injection volume was 10 μl. RESULTS： The TLC spots of C. chinensis and A. carvifolia were clear and well separated， negative control without interference. The linear range of artemisinin was 5.62-56.2 μg/ml（r＝0.999 4）；RSDs of precision， stability and reproducibility tests were lower than 1.0％； recovery was 97.46％-99.72％ （RSD＝0.75％，n＝6）. CONCLUSIONS： The satandard  can be used for the quality control of Qinglian ningxin capsule.