OBJECTIVE： To establish the quality standard for Huxitong oral solution. METHODS： TLC was conducted for the qualitative identification of Stemona japonica， Scutellaria baicalensis and Fructus arctii； HPLC was adopted for the content determination of baicalin： the column was Agilent Eclipse Plus-C18 with mobile phase of methanol-0.1％ phosphoric acid solution （48 ∶ 52，V/V） at a flow rate of 0.8 ml/min， the detection wavelength was 280 nm， column temperature was 25 ℃， injection volume was 20 μl. RESULTS： TLC spots of S. japonica， S. baicalensis and F. arctii were clear and well separated， with no interference in negative control. The linear range of baicalin was 0.378 0-3.779 5 μg （r＝0.999 9）； RSDs of precision， stability and reproducibility tests were lower than 2.0％； recovery was 96.52％-104.95％ （RSD＝1.28％，n＝9）. CONCLUSIONS： The improved standard can more effectively control the quality of Huxitong oral solution.