OBJECTIVE： To provide reference for the implementation of quality risk management in GSP of TCM trading enterprises. METHODS： The necessity of quality risk management in TCM trading enterprises was introduced； by using the method of quality risk management， based on hazard analysis and critical control point （HACCP） tool， according to the actual situation of TCM trading enterprises， four key links including the critical control points during purchasing， receiving and acceptance， storage and maintenance， exwarehouse and transportation were identified and controlled. RESULTS & CONCLUSIONS： It is recommended that TCM trading enterprises take corrective measures aiming at the above four key links of risk control points like whether the procurement link was lawful and legal； how to control TCM acceptance quality； whether TCM maintenance method was valid； whether transportation and distribution affected the quality of goods. For this purpose， procurement link should be based on the establishment of legal purchase channels； the experience of TCM appearance and property acceptance should be gathered in receiving and acceptance link to guarantee the quality of warehoused drugs based on the requirements of the newly revised GSP； storage and maintenance link should take an effective control of temperature and humidity， and carry out the scientific maintenance； exwarehouse and transportation link should highlight the “green logistics”， accomplishing quality and non-pollution.