OBJECTIVE： To provide reference for the safe and rational drug use for children. METHODS： Information management system was used to investigate the use of essential medicines system variety in stock in 2015 and analyze the medication information for children in the drug instructionsin our hospital in 2015. RESULTS： Only 201 kinds of medicines belonged to children’s medicines in all the 685 kinds of medicines in our hospital. And 89 kinds （44.28％） of medicines belonged to essential medicine system among the 201 kinds of children’s medicines， in which， 78 （87.60％） showed complete medication information for children； 112 kinds （55.72％） of medicines belonged to non-essential medicine system， in which， 38（33.93％） showed complete medication information for children. The proportions of showing complete medication information for children in the essential medicines and in its chemicals， biological products， injections and oral preparations were higher than non-essential medicines， the differences were statistically significant （P＜0.05）. Only 41 kinds of medicines belonged to child-specific medicines among the 201 children’s medicines； 62 showed complete medication information for children in the 73 kinds of essential medicines among the non-child-specific medicines； only 13 showed complete medication information for children in the 87 kinds of non-essential medicines， the proportion of showing complete medication information for children in essential medicines among the non-child-specific medicines was higher than non-essential medicines， the difference was statistically significant （P＜0.05）. CONCLUSIONS： The use proportion of essential medicine system variety for children’s medicines is high in our hospital； but there are lacking of child-specific medicines and the medication information for children is insufficient. However， compared with non-essential medicines for children， the essential medicines show better medication information for children in aspects of types， dosage form distribution and non-child-specific medicines， and it is suitable for children.