OBJECTIVE： To optimize the forming technology of Xuesaitong drop pills， and to investigate the usable batche number of condensate oleum vaselini. METHODS： Taking the contents of Panax notoginseng saponins， ginsenoside Rg1 and notoginsenoside R1， weight variation， appearance and quality score as index， single factor test and central composite design-response surface method were used to optimize dripper diameter， dripping distance， dripping temperature， the temperature of condensate upper/lower layer. Using P. notoginseng saponins as control， the fingerprints of condensate were collected and compared after preparing 15 batches of Xuesaitong drop pills （500 thousand pills per batch） continuously， and the usable batche number of condensate were investigated. RESULTS： The optimized molding technology of dripping pills was that the dripper diameter 3.9/5.1 （inside/outside， mm/mm）， dripping distance 6 cm， dripping system temperature 80 ℃， the upper temperature of condensate 40 ℃， the lower temperature of condensate 10 ℃. Relative deviation of comprehensive score to predicted value were －1.37％， －1.71％， －1.51％ for 3 batches， respectively. On retention time position of each component in P. notoginseng saponins fingerprint， corresponding peak was not found in the fingerprint of 15 batches of condensate. CONCLUSIONS： The optimized molding technology of Xuesaitong dripping pills is stable and available. Condensate liquid paraffin can be used to prepare 15 batches of Xuesaitong dripping pills at least.