OBJECTIVE： To optimize enzymatic extraction technology of polysaccharide from Schisandra chinensis. METHODS： Using pH value of enzymatic extraction solution， the amount of enzyme， extraction temperature as response factor， S. chinensis polysaccharide as response value， on the basis of single-factor experiments， 3-factor， 5-level central composite experimental design was adopted for the experiment. Validation test was also conducted.  RESULTS： The optimal extraction technology was as pH value of 5.7， enzyme dosage of 1.3％， extraction temperature of 53 ℃. In validation test， the extraction rate of S. chinensis polysaccharide was 14.30％（RSD＝1.84％， n＝6）. CONCLUSIONS： The optimized extraction technology is simple， reasonable and stable， and can be used for the extraction of polysaccharide from S. chinensis.