OBJECTIVE: To compare the quality control index between Jinzhen Suanzao teabag and decoction, and explore the alternative supplement of teabag to decoction. METHODS: The test sample solutions of Jinzhen Suanzao teabag and decoction were prepared by hot-maceration method and water-decoction method. The contents of water soluble extract and total flavonoids were determined and compared between 2 kinds of preparation. The leaching rates of teabag were investigated at different soak time (0, 5, 10, 15, 20, 25, 30 min) to optimize soaking time. RESULTS: The average content of water soluble extract were 50.56% and 44.45% (P<0.05) respectively for the teabag and decoction. The total flavonoids content were 0.64 mg/g and 0.69 mg/g (P<0.05). The dissolution amount of teabag were increasing and leaching rate increased within first 20 min, and reached balance gradually 25 min later. CONCLUSIONS: According to the convenience of use and results of each index, the difference in quality control index is not great between 2 kinds of preparation. Teabag can be as the supplement of decoction.