OBJECTIVE: To observe the effects of epidural anesthesia analgesia on childbearing. METHODS: 197 delivery woman were randomly divided into observation group (95 cases) and control group (102 cases). Control group was given natural childbirth, and observation group was additionally given epidural anesthesia analgesia. Neonatal Apgar score (5 min), behavioral neurological score and VAS, mother-infant situation, the incidence of ADR were compared between 2 groups. RESULTS: There was no statistical significance in neonatal Apgar score and behavioral neurological score between 2 groups (P>0.05); VAS score and the rate of cesarean section in observation group was significantly lower than in control group, with statistical significance (P<0.05). There was no statistical significance in the incidence of postpartum hemorrhage, vaginal midwifery and asphyxia neonatorum (P>0.05). ADR as itchy skin, nausea and vomiting, headache, limb numbness of observation group were improved after symptomatic treatment. CONCLUSIONS: The epidural anesthesia analgesia have no effect on childbearing and can relieve labor pain with good safety.