OBJECTIVE： To investigate the dosage and consumption sum of opioid analgesic drug in Qingdao district. METHODS： The consumption data of drugs in 29 public hospitals at secondary or above level in Qingdao district were analyzed statistically by ABC analytic methods and defined daily dose methods. RESULTS： In ABC analysis， 5 kinds of class A drugs accounted for 20％ of the total number of species， and the percentage of consumption sum was 77.38％； 4 kinds of class B drugs accounted for 16.00％ of all species numbers， and the percentage of consumption sum was 11.98％； other 16 kinds of drugs accounted for 64.00％ of the total number of species， and the percentage of consumption sum was 10.64％. Oxycodone sustained-release tablets and Morphine sustained-release tablets with the highest DDDs consumed more health care costs， serial number ratio was 1.00， synchronization was good and conform to the actual needs of clinical work. CONCLUSIONS： The composition ratio of opioid analgesic drug costs is consistent with the theoretical value， significant discrepancy between cost and DDDs does not appear.