OBJECTIVE： To provide reference for improving the application ability of professional English for students majoring in pharmacy in  higher vocational education. METHODS： The career-oriented practical pharmaceutical English course and teaching system were constructed through the way of formulation of curriculum standards， establishment of teachers’ team， development of school-based teaching material， application of CBI theme teaching mode and variety teaching methods， and it was carried out among students majoring in pharmacy in 2011-2014 grades in our school. Besides， experimental and survey research were used for the evaluation of Proctical Pharmaceutical English. RESULTS： There was no significant difference in the academic achievement and questionnaire evaluation between 2 class before teaching（P＞0.05）； however， academic achievement and questionnaire evaluation were higher than 2 class after teaching， experimemal class higher than control class， the difference was statistically significant（P＜0.05）. CONCLUSIONS： The career-oriented Practical Pharmaceutical English course and teaching system is feasible and effective； compared with traditional teaching， it can inspire students' interest in English learning， improve the ability to use English in the work and motivate their comprehensive qualities.