OBJECTIVE： To understand the application of proprietary Chinese medicine by clinicians in integrated medical institutions， and provide reference for its rational use. METHODS： The questionnaire was designed， including related issues of proprietary Chinese medicine clinical application （such as medication basis of proprietary Chinese medicine， combined medication， clinical efficacy and its influencing factors， medication for special groups and so on） and suggestions； the questionnaires were delivered to the clinicians who worked in some second and third grade of integrated medical institutions located in southwestern regions and Chengdu， and the questionnaires was in the form of an anonymous； relevant data of available questionnaire were collected statistically； the application situation of proprietary Chinese medicines and the existence question were analyzed， and suggestions were put forward. RESULTS： Totally 300 questionnaires were sent out， 264 were effectively received， with effective rate of 88.0％. The clinicians involved in investigation were mainly in undergraduate， mostly the resident physicians and attending physician； only 6.8％ of the physicians received the training of basic theory of traditional Chinese medicine after work； 36.4％ physicians often prescribe proprietary Chinese medicines， and the medication basis was mainly in package insert （64.0％） and clinical experience （55.3％）； 51.1％ thought unclear indications affected the application of proprietary Chinese medicines， 64.0％ thought package insert can not meet clinical needs. In terms of answers in brief questions， the surveyed clinicians generally considered the package insert was too simple， which needed further perfected. CONCLUSIONS： The problems in clinical application of proprietary Chinese medicines should not be ignored. The relevant departments should strengthen the supervision of clinical application of proprietary Chinese medicines， and strengthen the re-evaluation of proprietary Chinese medicines market， as to provide data support for the continuous improvement of package insert. Medical institutions should carry out training timely for the physicians who prescribe proprietary Chinese medicines， the pharmacists should strengthen checking of proprietary Chinese medicines prescription and special prescription comment， and ensure prescription checking and comment play a active role in promoting rational drug use based on “proprietary Chinese medicines clinical application guiding principle”“prescription management method”.