OBJECTIVE： To explore the effects of risperidone combined Ningxin yizhi capsule on the cognitive function， neurologic function and living quality of cerebral infarction. METHODS： 110 patients with cerebral infarction were randomly divided into control group （55 cases） and observation group （55 cases）. All patients received aspirin， statins， penicillins， physical rehabilitation and other conventional treatment； based on it， control group orally received Risperidone tablet with initial dose of 0.5 mg， once a day， 1 week later， the amount of drugs was adjusted according to the patient's tolerance and conditions， 0.5 mg was increased every week， with maximum dose of less than 2 mg， no other antipsychotic drugs except risperidone. Observation group additionally received 0.9 g Ningxin yizhi capsule， 3 times a day. The treatment course for both groups was 2 months. Montreal cognitive assessment （MoCA） score， neurobehavioral cognitive status tests scale （NCSE）， National Institutes of Health Stroke Scale （NIHSS） score， activities of daily living scale （ADL） score and table of daily living-Barthel Index （Barthel-Index） before and after treatment， and the incidence of adverse reactions in 2 groups were observed. RESULTS： Before treatment， there were no significant differences in the MoCA scores， NCSE scores， NIHSS scores， ADL scores and Barthel-Index in 2 groups （P＞0.05）. After treatment， the MoCA scores， NCSE scores， ADL scores and Barthel-Index in 2 groups were significantly higher than before， and observation group was higher than control group， NIHSS scores were significantly lower than before， and observation group was lower than control group， the difference was statistically significant （P＜0.05）. And there was no significant difference in the incidence of adverse reactions （P＞0.05）. CONCLUSIONS： Based on the conventional treatment， risperidone combined Ningxin yizhi capsule can significantly improve the cognitive function， neurologic function and living quality of cerebral infarction， with good safety.