OBJECTIVE： To provide reference for rational use of TCM injection in the clinic. METHODS： The utilization of TCM injections in 34 hospitals from Nanjing area during 2012-2014 was analyzed statistically in respects of consumption sum， DDDs， DDC. The occurrence of ADR induced by TCM injections was also analyzed statistically in the First Affiliated Hospital of Nanjing Medical University. RESULTS： The consumption sum of TCM injections in 34 hospitals from Nanjing area during 2012- 2014 increased year by year； top 10 kinds of TCM injections mainly were anti-tumor drugs and cardio-cerebrovascular drugs in 2014， and each of them involved 4 categories and their consumption sum accounted for 46.08％ and 32.59％， respectively. Total consumption sum of anti-tumor TCM injections increased slowly， while those of cardio-cerebrovascular drugs， antibiosis and antiphlogosis increased rapidly. Lentinan injection steadily took up the top in the list of consumption sum and DDDs of single type， its DDC was the lowest and B/A＝1.00. In the First Affiliated Hospital of Nanjing Medical University， most of ADR was induced by Xiyanping injection （27 cases， 45.00％）. CONCLUSIONS： The type of TCM injections keep stable in 34 hospitals from Nanjing area during 2012-2014， mainly involving anti-tumor drugs and cardio-cerebrovascular drugs which were used widely. Clinic should strengthen dialectial therapy close monitoring and attch improtance to the rational use of TCM injections.