OBJECTIVE：To establish the GC specific chromatogram of Goupi cream. METHODS： Gas chromatography was performed on the column of fused silica capillary column by programmed temperature， injection temperature was 220 ℃， detector was hydrogen flame ionization detector with temperature of 250 ℃， the injection volume was 1 μl and split ratio of 20 ∶ 1. The eugenol chromatographic peak was used as reference peak to determine the 32 batches of Goupi cream from 5 enterprises， TCM fingerprint similarity calculation software （2009 edition） was conducted for the common peaks identification and similarity evaluation， and the specific chromatogram cluster analysis of 32 batches of samples. RESULTS： There were totally 11 common peaks in the 32 batches of Goupi cream， the 32 batches of samples from different enterprises showed low similarity and could be clustered into 5 types. CONCLUSIONS： The established specific chromatogram is specific and stable， and can provide reference for the quality evaluation and control of Goupi cream.